Publikationen

2020

INFLAMMATORY BOWEL DISEASES

Volume: 26

Published: January 2020

DOI: 10.1093/ibd/izz142

Iris Stolzer, Valentina Kaden-Volynets, Barbara Ruder, Marilena Letizia, Miriam Bittel, Philipp Rausch, Marijana Basic, André Bleich, John F Baines, Markus F Neurath, Stefan Wirtz, Carl Weidinger, Stephan C Bischoff, Christoph Becker, Claudia Günther

Environmental Microbial Factors Determine the Pattern of Inflammatory Lesions in a Murine Model of Crohn’s Disease–Like Inflammation

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY

Volume: 17

Published: January 2020

DOI: 10.1038/s41575-019-0228-5

Jonathan L. Digby-Bell, Raja Atreya, Giovanni Monteleone, Nick Powell

Interrogating host immunity to predict treatment response in inflammatory bowel disease

EUROPEAN JOURNAL OF IMMUNOLOGY

Volume:

Published: February 2020

DOI: 10.1002/eji.201948474

Alexander Beller, Andrey Kruglov, Pawel Durek, Victoria von Goetze, Katharina Werner, Gitta Anne Heinz, Justus Ninnemann, Katrin Lehmann, René Maier, Ute Hoffmann, René Riedel, Kevin Heiking, Jakob Zimmermann, Britta Siegmund, Mir‐Farzin Mashreghi, Andreas Radbruch, Hyun‐Dong Chang

Specific microbiota enhances intestinal IgA levels by inducing TGF-β in T follicular helper cells of Peyer’s patches in mice.

FRONTIERS IN IMMUNOLOGY

Volume: 11

Published: February 2020

DOI: 10.3389/fimmu.2020.00209

Markus Kindermann, Lisa Knipfer, Stephanie Obermeyer, Uwe Müller, Gottfried Alber, Christian Bogdan, Ulrike Schleicher, Markus F. Neurath, Stefan Wirtz

Group 2 Innate Lymphoid Cells (ILC2) Suppress Beneficial Type 1 Immune Responses During Pulmonary Cryptococcosis.

CANCERS

Volume: 12

Published: February 2020

DOI: 10.3390/cancers12020488

Grazia Carbotti, Andrea Petretto, Elisabeth Naschberger, Michael Stürzl, Stefania Martini, Maria Cristina Mingari, Gilberto Filaci, Silvano Ferrini, Marina Fabbi

Cytokine-Induced Guanylate Binding Protein 1 (GBP1) Release from Human Ovarian Cancer Cells

2019

VISCERAL MEDICINE

Volume: 35

Published: January 2019

DOI: 10.1159/000496838

Khalil M., Zhang Z., Engel M.A.

Neuro-Immune Networks in Gastrointestinal Disorders

INT. JOURNAL OF CANCER
Volume: 0
Published: January 2019
DOI: 10.1002/ijc.32137.
Susan Bengs, Eugenia Becker, Philipp Busenhart, Marianne R. Spalinger, Tina Raselli, Stephanie Kasper, Silvia Lang, Kirstin Atrott, Celine Mamie, Stephan R. Vavricka, Lotta von Boehmer, Alexander Knuth, Anne Tuomisto, Markus J. Mäkinen, Petr Hruz, Matthias Turina, Andreas Rickenbacher, Henrik Petrowsky, Achim Weber, Pascal Frei, Marcel Halama, Gisli Jenkins, Dean Sheppard, Roland S. Croner, Jan Christoph, Nathalie Britzen-Laurent, Elisabeth Naschberger, Vera Schellerer, Michael Stürzl, Michael Fried, Gerhard Rogler, Michael Scharl

β6-integrin serves as a novel serum tumor marker for colorectal carcinoma

JOURNAL OF LEUKOCYTE BIOLOGY

Volume: 105

Published: January 2019

DOI: 10.1002/JLB.HI0718-249RR

Aparna Mahajan, Anika Grüneboom, Lenka Petru, Malgorzata J. Podolska, Lasse Kling, Christian Maueröder, Florian Dahms, Silke Christiansen, Lochnit Günter, Veit Krenn, Anselm Jünemann, Felix Bock, Christine Schauer, Georg Schett, Bettina Hohberger, Martin Herrmann, Luis E. Muñoz

Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil-rich ocular surface

NATURE IMMUNOLOGY

Volume: 20

Published: January 2019

DOI: 10.1038/s41590-018-0298-5

Sebastian Zundler, Emily Becker, Marta Spocinska, Monique Slawik, Loreto Parga-Vidal, Regina Stark, Maximilian Wiendl, Raja Atreya, Timo Rath, Moritz Leppkes, Kai Hildner, Rocío López-Posadas, Sören Lukassen, Arif B. Ekici, Clemens Neufert, Imke Atreya, Klaas P. J. M. van Gisbergen, Markus F. Neurath

Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation

NATURE 

Volume: 566
Published: January 2019
DOI:10.1038/s41586-019-0899-7.
Konrad Gronke, Pedro P. Hernández, Jakob Zimmermann, Christoph S. N. Klose, Michael Koefoed-Branzk, Fabian Guendel, Mario Witkowski, Caroline Tizian, Lukas Amann, Fabian Schumacher, Hansruedi Glatt, Antigoni Triantafyllopoulou, Andreas Diefenbach

Interleukin-22 protects intestinal stem cells against genotoxic stress

FRONTIERS IN IMMUNOLOGY

Volume:10

Published: February 2019

DOI: 10.3389/fphar.2019.00039

Charlotte Lichnog, Sha Klabunde, Emily Becker, Franklin Fuh, Philipp Tripal, Raja Atreya, Entcho Klenske, Rich Erickson, Henry Chiu, Chae Reed, Shan Chung, Clemens Neufert, Imke Atreya, Jacqueline McBride, Markus F. Neurath, Sebastian Zundler

Cellular Mechanisms of Etrolizumab Treatment in Inflammatory Bowel Disease

STEM CELL RESEARCH

Volume: 35

Published: February 2019

DOI: 10.1016/j.scr.2019.101383

Marco Bardenbacher, Barbara Ruder, Nathalie Britzen-Laurent, Benjamin Schmid, Maximilian Waldner, Elisabeth Naschberger, Michael Scharl, Werner Müller, Claudia Günther, Christoph Becker, Michael Stürzl, Philipp Tripal

Permeability analyses and three dimensional imaging of interferon gamma-induced barrier disintegration in intestinal organoids

SEMINARS IN IMMUNOLOGY

Volume: 41

Published: February 2019

DOI: 10.1016/j.smim.2019.02.001

Imke Atreya, Markus Kindermann, Stefan Wirtz

Innate lymphoid cells in intestinal cancer development

NATURE IMMONOLOGY

Volume: 0

Published: February 2019
DOI: 10.1038/s41590-019-0316-2.
Christian Neumann, Jonas Blume, Urmi Roy, Peggy P. Teh, Ajithkumar Vasanthakumar, Alexander Beller, Yang Liao, Frederik Heinrich, Teresita L. Arenzana, Jason A. Hackney, Celine Eidenschenk, Eric J. C. Gálvez, Christina Stehle, Gitta A. Heinz, Patrick Maschmeyer, Tom Sidwell, Yifang Hu, Derk Amsen, Chiara Romagnani, Hyun-Dong Chang, Andrey Kruglov, Mir-Farzin Mashreghi, Wei Shi, Till Strowing, Sascha Rutz, Axel Kallies, Alexander Scheffold
c-Maf-dependent T-reg-cell control of intestinal T-H-17 cells and IgA establishes host-microbiota homeostasis
CELL

Volume: 0

Published: February 2019
DOI:10.1016/j.cell.2019.01.041.
Petra Bacher, Thordis Hohnstein, Eva Beerbaum, Marie Röcker, Matthew G. Blango, Svenja Kaufmann, Jobst Röhmel, Patience Eschenhagen, Claudia Grehn, Kathrin Seidel, Volker Rickerts, Laura Lozza, Ulrik Stervbo, Mikalai Nienen, Nina Babel, Julia Milleck, Mario Assenmacher, Oliver A. Cornely, Maren Ziegler, Hilmar Wisplinghoff, Guido Heine, Margitta Worm, Britta Siegmund, Jochen Maul, Petra Creutz, Christoph Tabeling, Chistoph Ruwwe-Glösenkamp, Leif E. Sander, Christoph Knosalla, Sascha Brunke, Bernhard Hube, Olaf Kniemeyer, Axel A. Brakhage, Carsten Schwarz, Alexander Scheffold
Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans

BRAIN STIMULATION

Volume: 12

Published: March 2019

DOI: 10.1016/j.brs.2019.03.001.

Lars Neeb, Arian Bayer, Kian-Elias Bayer, Annabelle Farmer, Jochen B. Fiebach, Britta Siegmund, Magdalena Sarah Volz

Transcranial direct current stimulation in inflammatory bowel disease patients modifies resting-state functional connectivity: A RCT

JOURNAL OF CROHN´S AND COLITIS

Volume: 13

Published: April 2019

DOI: 10.1093/ecco-jcc/jjz036

Franziska Schmidt, Katja Dahlke, Arvind Batra, Jacqueline Keye, Hao Wu, Marie Friedrich, Rainer Glauben, Christiane Ring, Gunnar Loh, Monika Schaubeck, Hubert Hackl, Zlatko Trajanoski, Michael Schumann, Anja A Kühl, Michael Blaut, Britta Siegmund

Microbial Colonization in Adulthood Shapes the Intestinal Macrophage Compartment 

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Volume: 20

Published: April 2019

DOI: 10.3390/ijms20081887

Barbara Ruder, Raja Atreya, Christoph Becker

Tumour Necrosis Factor Alpha in Intestinal Homeostasis and Gut Related Diseases

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

Volume:

Published: April 2019

DOI: 10.3791/59043

Anja Schulz-Kuhnt, Sebastian Zundler, Anika Grüneboom, Clemens Neufert, Stefan Wirtz, Markus F. Neurath, Imke Atreya

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

ADVANCED SCIENCE

Volume: 6

Published: April 2019

DOI: 10.1002/advs.201801735

Ashwathama Dilipkumar, Alaa Al‐Shemmary, Lucas Kreiß, Kristian Cvecek, Birgitta Carlé, Ferdinand Knieling, Jean, Gonzales Menezes, Oana‐Maria Thoma, Michael Schmidt, Markus F. Neurath, Maximilian Waldner, Oliver Friedrich, Sebastian Schürmann

Label-Free Multiphoton Endomicroscopy for Minimally Invasive In Vivo Imaging

INFLAMMATORY BOWEL DISEASE

Volume: 69

Published: April 2019

DOI: 10.1136/gutjnl-2018-316772

Lena Schleier, Maximilian Wiendl, Karin HeidbredeR, Marie-Theres Binder, Raja Atreya, Timo Rath, Emily Becker, Anja Schulz-Kuhnt, Annette Stahl, Lisa Lou Schulze, Karen Ullrich, Simon F Merz, Lea Bornemann, Matthias Gunzer, Alastair J M Watson, Clemens Neufert, Imke Atreya, Markus F Neurath, Sebastian Zundler

Non-classical monocyte homing to the gut via α4β7 integrin mediates macrophage-dependent intestinal wound healing

FRONTIERS IN PHARMACOLOGY

Volume: 10

Published: April 2019

DOI: 10.3389/fphar.2019.00314

Patrizio Scarozza, Heike Schmitt, Giovanni Monteleone, Markus F. Neurath, Raja Atreya

Oligonucleotides—A Novel Promising Therapeutic Option for IBD

GENOME MEDICINE

Volume: 11

Published: May 2019

DOI: 10.1186/s13073-019-0638-6

Francesca Finotello, Clemens Mayer, Christina Plattner, Gerhard Laschober, Dietmar Rieder, Hubert Hackl, Anne Krogsdam, Zuzana Loncova, Wilfried Posch, Doris Wilflingseder, Sieghart Sopper, Marieke Ijsselsteijn, Thomas P. Brouwer, Douglas Johnson, Yaomin Xu, Yu Wang, Melinda E. Sanders, Monica V. Estrada, Paula Ericsson-Gonzalez, Pornpimol Charoentong, Justin Balko, Noel Filipe da Cunha Carvalho de Miranda, Zlatko Trajanoski

Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data.

DIGESTIVE AND LIVER DISEASE

Volume: 51

Published: June 2019

DOI: 10.1016/j.dld.2019.02.020

Claudia Günther, Teresa Brevini, Fotios Sampaziotis, Markus F. Neurath

What gastroenterologists and hepatologists should know about organoids in 2019

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY

Volume: 12

Published: June 2019

DOI: 10.1177/1756284819856865

Entcho Klenske , Christian Bojarski, Maximilian Waldner, Timo Rath, Markus F. Neurath, Raja Atreya

Targeting mucosal healing in Crohn’s disease: what the clinician needs to know

NATURE REVIEWS NEPHROLOGY

Volume: 15

Published: June 2019

DOI: 10.1038/s41581-019-0163-2

Christoph Daniel, Moritz Leppkes, Luis E. Muñoz, Gunnar Schley, Georg Schett, Martin Herrmann

Extracellular DNA traps in inflammation, injury and healing

NATURE IMMUNOLOGY

Volume: 20

Published: June 2019

DOI: 10.1038/s41590-019-0415-0

Markus F. Neurath

Targeting immune cell circuits and trafficking in inflammatory bowel disease

INFLAMMATORY BOWEL DISEASE

Volume: 26

Published: July 2019

DOI: 10.1093/ibd/izz142

Iris Stolzer, Valentina Kaden-Volynets, Barbara Ruder, Marilena Letizia, Miriam Bittel, Philipp Rausch, Marijana Basic, André Bleich, John F Baines, Markus F Neurath, Stefan Wirtz, Carl Weidinger, Stephan C Bischoff, Christoph Becker, Claudia Günther

Environmental Microbial Factors Determine the Pattern of Inflammatory Lesions in a Murine Model of Crohn’s Disease – Like Inflammation

GENOME MEDICINE

Volume: 11

Published: July 2019

DOI: 10.1186/s13073-019-0662-6

Noel F. C. C. de Miranda, Zlatko Trajanoski

Advancing cancer immunotherapy: a vision for the field

IMMUNITY

Volume: 51

Published: September 2019

DOI: 10.1016/j.immuni.2019.07.002

Luis E. Muñoz, Sebastian Boeltz, Rostyslav Bilyy, Christine Schauer, Aparna Mahajan, Navena Widulin, Anika Grüneboom, Irmgard Herrmann, Edgyda Boada, Manfred Rauh, Veit Krenn, Mona H. C. Biermann, Malgorzata J. Podolska, Jonas Hahn, Jasmin Knopf, Christian Maueröder, Solomiya Paryzhak, Tetiana Dumych, Yi Zhao, Markus F. Neurath, Markus H. Hoffmann, Tobias A. Fuchs, Moritz Leppkes, Georg Schett, Martin Herrmann

Neutrophil Extracellular Traps Initiate Gallstone Formation

GUT

Volume: 68

Published: September 2019

DOI: 10.1136/gutjnl-2018-317977

Sebastian Zundler, Emily Becker, Lisa Lou Schulze, Markus F Neurath

Immune cell trafficking and retention in inflammatory bowel disease: mechanistic insights and therapeutic advances

JOURNAL OF LEUKOCYTE BIOLOGY

Volume: 106

Published: September 2019

DOI: 10.1002/JLB.3AB0918-370R

Malgorzata J. Podolska, Aparna Mahajan, Jonas Hahn, Jasmin Knopf, Christian Maueröder, Lenka Petru, Marc Ullmann, Georg Schett, Moritz Leppkes, Martin Herrmann, Luis E. Muñoz, Christine Schauer

Treatment with DNases rescues hidden neutrophil elastase from aggregated NETs

MEDICINE

Volume: 98

Published: September 2019

DOI: 10.1097/MD.0000000000017017

Kian-Elias Bayer, Lars Neeb, Arian Bayer, Jakob Johann Wiese, Britta Siegmund, Magdalena Sarah Prüß

Reduction of intra-abdominal pain through transcranial direct current stimulation: A systematic review

FRONTIERS IN IMMUNOLOGY

Volume: 10

Published: September 2019

DOI: 10.3389/fimmu.2019.02176

Jasmin Knopf, Moritz Leppkes, Georg Schett, Martin Herrmann, Luis E. Munoz

Aggregated NETs Sequester and Detoxify Extracellular Histones

NATURE REVIEWS GENETICS

Volume: 20

Published: September 2019

DOI: 10.1038/s41576-019-0166-7

Francesca Finotello, Dietmar Rieder, Hubert Hackl, Zlatko Trajanoski

Next-generation computational tools for interrogating cancer immunity

SEMINARS IN IMMUNPATHOLOGY

Volume: 41

Published: September 2019

DOI: 10.1007/s00281-019-00756-1

Heike Schmitt, Clemens Neufert, Markus F. Neurath, Raja Atreya

Resolution of Crohn´s disease

AMERICAN JOURNAL OF PHYSIOLOGY – GASTROINTESTINAL AND LIVER

Volume: 317

Published: October 2019

DOI: 10.1152/ajpgi.00297.2018

Valentina Kaden-Volynets, Claudia Günther, Julia Zimmermann, Julia Beisner, Christoph Becker, Stephan C. Bischoff

Deletion of the Casp8 gene in mice results in ileocolitis, gut barrier dysfunction, and malassimilation, which can be partially attenuated by inulin or sodium butyrate

JOURNAL OF CROHN´S AND COLITIS

Volume:

Published: October 2019

DOI: 10.1093/ecco-jcc/jjz170

Heike Schmitt, Julia Ulmschneider, Ulrike Billmeier, Michael Vieth, Patrizio Scarozza, Sophia Sonnewald, Stephen Reid, Imke Atreya, Timo Rath, Sebastian Zundler, Melanie Langheinrich, Jürgen Schüttler, Arndt Hartmann, Thomas Winkler, Charlotte Admyre, Thomas Knittel, Christine Dieterich Johansson, Arezou Zargari, Markus F. Neurath, Raja Atreya
 

The TLR9 agonist cobitolimod induces IL10 producing wound healing macrophages and regulatory T cells in ulcerative colitis

FRONTIERS IN IMMUNOLOGY

Volume:10

Published: October 2019

DOI: 10.3389/fimmu.2019.02481

Stefanie Gößwein, Aylin Lindemann, Aparna Mahajan, Christian Maueröder, Eva Martini, Jay Patankar, Georg Schett, Christoph Becker, Stefan Wirtz, Nora Naumann-Bartsch, Marco E. Bianchi, Peter A. Greer, Günter Lochnit, Martin Herrmann, Markus F. Neurath, Moritz Leppkes

Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation

JOURNAL OF CLINICAL INVESTIGATION

Volume: 129

Published: November 2019

DOI: 10.1172/JCI124884

Victoria Langer, Eugenia Vivi, Daniela Regensburger, Thomas H. Winkler, Maximilian J. Waldner, Timo Rath, Benjamin Schmid, Lisa Skottke, Somin Lee, Noo Li Jeon, Thomas Wohlfahrt, Viktoria Kramer, Philipp Tripal, Michael Schumann, Stephan Kersting, Claudia Handtrack, Carol I. Geppert, Karina Suchowski, Ralf H. Adams, Christoph Becker, Andreas Ramming, Elisabeth Naschberger, Nathalie Britzen-Laurent, Michael Stürzl

IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin–directed vascular barrier disruption

GASTROENTEROLOGY

Volume: 157

Published: November 2019

DOI: 10.1053/j.gastro.2019.07.007

Rocío López-Posadas, PetraFastancz, Luz del Carmen Martínez-Sánchez, Julia Panteleev-Ivlev, Veronika Thonn, Tatyana Kisseleva, Lukas S. Becker, Anja Schulz-Kuhnt, Sebastian Zundler, Stefan Wirtz, Raja Atreya, Birgitta Carlé, Oliver Friedrich, Sebastian Schürmann, Maximilian J. Waldner, Clemens Neufert, Cord H. Brakebusch, Martin O. Bergö, Markus F. Neurath, Imke Atreya

Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice

GASTROENTEROLOGY

Volume: 157

Published: November 2019

DOI: 10.1053/j.gastro.2019.07.031

Claudia Günther, Barbara Ruder, Iris Stolzer, Heidrun Dorner, Gui-Wei He, Mircea Teodor Chiriac, Konrad Aden, Anne Strigli, Miriam Bittel, Sebastian Zeissig, Philip Rosenstiel, Raja Atreya, Markus F. Neurath, Stefan Wirtz, Christoph Becker

Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn’s Disease

NATURE COMMUNICATIONS

Volume: 10

Published: November 2019

DOI: 10.1038/s41467-019-13559-7

Jörn F. Ziegler, Chotima Böttcher, Marilena Letizia, Cansu Yerinde, Hao Wu, Inka Freise, Yasmina Rodriguez-Sillke, Ani K. Stoyanova, Martin E. Kreis, Patrick Asbach, Desiree Kunkel, Josef Priller, Ioannis Anagnostopoulos, Anja A. Kühl, Konstanze Miehle, Michael Stumvoll, Florian Tran, Broder Fredrich, Michael Forster, Andre Franke, Christian Bojarski, Rainer Glauben, Britt-Sabina Löscher, Britta Siegmund, Carl Weidinger 

Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease

IMMUNITY

Volume: 51

Published: November 2019

DOI: 10.1016/j.immuni.2019.10.011

Markus F. Neurath, Mircea T. Chiriac

Targeting Immune Cell Wiring in Ulcerative Colitis

CELL DEATH & DISEASE

Volume: 10

Published: November 2019

DOI: 10.1038/s41419-019-2115-y

Miriam Bittel, Andreas E. Kremer, Michael Stürzl, Stefan Wirtz, Iris Stolzer, Markus F. Neurath, Gianna Ballon, Claudia Günther

Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure

FRONTIERS IN IMMUNOLOGY

Volume: 10

Published: November 2019

DOI: 10.3389/fimmu.2019.02718

Cansu Yerinde, Britta Siegmund, Rainer Glauben, Carl Weidinger

Metabolic Control of Epigenetics and Its Role in CD8+ T Cell Differentiation and Function

EXPERT OPINION ON BIOLOGICAL THERPY

Volume: 20

Published: November 2019

DOI: 10.1080/14712598.2020.1695775

Clemens Neufert, Markus F. Neurath, Raja Atreya

Rationale for IL-36 receptor antibodies in ulcerative colitis

CURRENT OPINION IN GASTROENTEROLOGY

Volume: 35

Published: November 2019

DOI:10.1097/MOG.0000000000000579

Sebastian Zundler, Maximilian Wiendl, Markus F. Neurath

Anti-trafficking agents in the treatment of inflammatory bowel disease

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Volume: 20

Published: November 2019

DOI: 10.3390/ijms20225597

Deborah Delbue, Danielle Cardoso-Silva, Federica Branchi, Alice Itzlinger, Marilena Letizia, Britta Siegmund, Michael Schumann

Celiac Disease Monocytes Induce a Barrier Defect in Intestinal Epithelial Cells

SEMINARS IN IMMUNOPATHOLOGY

Volume: 41

Published: November 2019

DOI: 10.1007/s00281-019-00771-2

Markus F. Neurath

Resolution of inflammation: from basic concepts to clinical application

SENSORS AND ACTUATORS

Volume: 301

Published: December 2019

DOI: 10.1016/j.snb.2019.127121

Lucas Kreiß, Martin Hohmann, Florian Klämpfl, Sebastian Schürmann, Faramarz Dehghani, Michael Schmidt, Oliver Friedrich, Lorenz Büchler

Diffuse reflectance spectroscopy and Raman spectroscopy for label-free molecular characterization and automated detection of human cartilage and subchondral bone

SCIENTIFIC REPORTS

Volume: 9

Published: December 2019

DOI: 10.1038/s41598-019-55852-x

Chotima Böttcher, Camila Fernández-Zapata, Stephan Schlickeiser, Desiree Kunkel, Axel R. Schulz, Henrik E. Mei, Carl Weidinger, René M. Gieß, Susanna Asseyer, Britta Siegmund, Friedemann Paul, Klemens Ruprecht, Josef Priller 

Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis

SEMINARS IN ARTHRITIS AND RHEUMATISM

Volume: 49

Published: December 2019

DOI: 10.1016/j.semarthrit.2019.09.011

Moritz Leppkes, Maximilian Schick, Bettina Hohberger, Aparna Mahajan, Jasmin Knopf, Georg Schett, Luis E. Munoz, Martin Herrmann

Updates on NET formation in health and disease

NATURE MEDICINE

Volume: 25

Published: December 2019

DOI: 10.1038/s41591-019-0669-y

Adrian P. Regensburger, Lina M. Fonteyne, Jörg Jüngert, Alexandra L. Wagner, Teresa Gerhalter, Armin M. Nagel, Rafael Heiss, Florian Flenkenthaler, Matthias Qurashi, Markus F. Neurath, Nikolai Klymiuk, Elisabeth Kemter, Thomas Fröhlich, Michael Uder, Joachim Woelfle, Wolfgang Rascher, Regina Trollmann, Eckhard Wolf, Maximilian J. Waldner, Ferdinand Knieling 

Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy

2018

FRONTIERS IN IMMUNOLOGY

Volume: 9

Published: May 2018
DOI: 10.3389/fimmu.2018.01171
Moritz Leppkes, Britta Siegmund and Christoph Becker
Editorial: Immune-Epithelial Crosstalk in Inflammatory Bowel Diseases and Mucosal Wound Healing.
FRONTIERS IN IMMUNOLOGY

Volume: 9

Published: July 2018
DOI: 10.3389/fimmu.2018.01700
Timo Rath, Ulrike Billmeier, Fulvia Ferrazzi, Michael Vieth, Arif Ekici, Markus F. Neurath, Raja Atreya
Effects of Anti-Integrin Treatment With Vedolizumab on Immune Pathways and Cytokines in Inflammatory Bowel Diseases
NATURE IMMUNOLOGY

Volume: 19

Published: August 2018

DOI: 10.1038/s41590-018-0163-6

Quirin Hammer, Timo Rückert & Chiara Romagnani

Natural killer cell specificity for viral infections
BIOCHEMICAL JOURNAL

Volume: 475

Published: August 2018

DOI: 10.1042/BCJ20180123
Bea Unterer, Veit Wiesmann, Mekala Gunasekaran, Heinrich Sticht, Clara Tenkerian, Jürgen Behrens, Marina Leone, Felix B. Engel, Nathalie Britzen-Laurent, Elisabeth Naschberger, Thomas Wittenberg, Michael Stürzl
IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD
MUCOSAL IMMUNOLOGY

Volume: 11

Published: August 2018

DOI: 10.1038/s41385-018-0068-6

Barbara Ruder, Vinay Murtadak, Michael Stürzl, Stefan Wirtz, Ute Distler, Stefan Tenzer, Mousumi Mahapatro, Florian R. Greten, Yinling Hu, Markus F. Neurath, Ethel Cesarman, Gianna Ballon, Claudia Günther, Christoph Becker
Chronic intestinal inflammation in mice expressing viral Flip in epithelial cells

JOURNAL OF CROHN´S AND COLITIS

Volume: 13

Published: October 2018

DOI: 10.1093/ecco-jcc/jjy146

Lea I Kredel, Lisa J Jödicke, Alexander Scheffold, Jörn Gröne, Rainer Glauben, Ulrike Erben, Anja A Kühl, Britta Siegmund

T-cell Composition in Ileal and Colonic Creeping Fat – Separating Ileal from Colonic Crohn’s Disease

FRONT IMMUNOLOGY

Volume: 9

Published: October 2018
DOI:10.3389/fimmu.2018.01974
Carl Weidinger, Jörn F. Ziegler, Marilena Letizia, Franziska Schmidt, Britta Siegmund
Adipokines and Their Role in Intestinal Inflammation
LANCET GASTRO. and HEPAT.

Volume: 3

Published: November 2018
DOI:10.1016/S2468-1253(18)30265-6
Raja Atreya, Markus F. Neurath
Mechanisms of molecular resistance and predictors of response to biological therapy in inflammatory bowel disease
NUTRIENTS
Volume: 10
Published: November 2018
DOI: 10.3390/nu10111796.
Alice Itzlinger, Federica Branchi, Luca Elli, Michael Schumann
Gluten-Free Diet in Celiac Disease – Forever and for All?
IMMUNOLOGICAL REVIEWS

Volume: 286

Published: November 2018
DOI:10.1111/imr.12712.
Christina Stehle, Daniela C. Hernández, Chiara Romagnani
Innate lymphoid cells in lung infection and immunity

MUCOSAL IMMUNOLOGY

Volume: 12

Published: November 2018

DOI: 10.1038/s41385-018-0107-3

Christoph Schubart, Branislav Krljanac, Manuel Otte, Cornelia Symowski, Eva Martini, Claudia Günther, Christoph Becker, Christoph Daniel, David Voehringer

Selective expression of constitutively activated STAT6 in intestinal epithelial cells promotes differentiation of secretory cells and protection against helminths

GASTROENTEROLOGY

Volume: 0

Published: November 2018
DOI:10.1053/j.gastro.2018.11.029.
Kristina Scheibe, Christina Kersten, Anabel Schmied, Michael Vieth, Tatjana Primbs, Birgitta Carlé, Ferdinand Knieling, Jing Claussen, Alexander C. Klimowicz, Jie Zheng, Patrick Baum, Sebastian Meyer, Sebastian Schürmann, Oliver Friedrich, Maximilian J. Waldner, Timo Rath, Stefan Wirtz, George Kollias, Arif B. Ekici, Raja Atreya, Ernest L. Raymond, M. Lamine Mbow, Markus F. Neurath, Clemens Neufert
Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation
INT J OF COLORECTAL DISEASE
Volume: 34
Published: November 2018
DOI: 10.1007/s00384-018-3198-0.
Vera S. Schellerer, Melanie C. Langheinrich, Veronika Zver, Robert Grützmann, Michael Stürzl, Olaf Gefeller, Elisabeth Naschberger, Susanne Merkel
Soluble intercellular adhesion molecule-1 is a prognostic marker in colorectal carcinoma
AMERICAN JOURNAL GASTROENTEROLOGY

Volume: 113

Published: December 2018
DOI: 10.1038/s41395-018-0394-z.
Sebastian Zundler, Lisa Dietz, Klaus Matzel, Carol-Immanuel Geppert, Emily Becker, Timo Rath, Markus F. Neurath, Raja Atreya
Successful Long-term Treatment of Diversion Colitis with Topical Coconut Oil Application
J OF ALLERGY & CLINICAL IMMUNOLOGY

Volume: 142

Published: December 2018
DOI: 10.1016/j.jaci.2018.10.016.
Petra Bacher, Alexander Scheffold
The effect of regulatory T cells on tolerance to airborne allergens and allergen immunotherapy
THERANOSTICS

Volume: 8

Published: December 2018
DOI: 10.7150/thno.26013
Dennis Jung, Rafael Heiss, Viktoria Kramer, Oana-Maria Thoma, Adrian P. Regensburger, Wolfgang Rascher, Michael Uder, Markus F. Neurath, Ferdinand Knieling, Maximilian J. Waldner
Contrast-Enhanced μCT for Visualizing and Evaluating Murine Intestinal Inflammation
NATURE NEUROSCIENCE

Volume: 22

Published: December 2018
DOI: 10.1038/s41593-018-0290-2.
Chotima Böttcher, Stephan Schlickeiser, Marjolein A. M. Sneeboer, Desiree Kunkel, Anniki Knop, Evdokia Paza, Pawel Fidzinski, Larissa Kraus, Gijsje J. L. Snijders, René S. Kahn, Axel R. Schulz, Henrik E. Mei, NBB-Psy, Elly M. Hol, Britta Siegmund, Rainer Glauben, Eike J. Spruth, Lot D. de Witte, Josef Priller
Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry